The patient is a 49-year-old woman who presented with headaches and visual changes. Brain MRI showed a large suprasellar mass which was predominantly solid and with avid enhancment. H&E micrographs are shown.  Which of the following genetic alterations is commonly seen in this tumor?


A. Beta-catenin mutation 

B. BRAF-KIAA1549 fusion

C. TP53 mutation

D. BRAF mutation 


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3 photo(s) Updated on: 07/31/2023

Submitting pathologist

Nima Sharifai, MD, PhD

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