The patient is a 43-year-old man with fatigue. A Complete Blood Count (CBC) shows the following:

Diff

Photomicrographs of the peripheral blood smear, H&E sections of bone marrow core biopsy and clot section, and Giemsa stain of bone marrow smears are shown.  

What is your diagnosis?

A. Systemic mastocytosis

B. Myeloid/lymphoid neoplasm with PDGFRA fusion gene

C. Acute myeloid leukemia with inv(16)/CBFB rearrangement 

D. Chronic eosinophilic leukemia, NOS