A 35-year-old man has slow-growing lymphadenopathy and B-symptoms. H&E micrographs and an S-100 immunostain of a lymph node are shown. 

 

What is your diagnosis and what is the most likely mutation.

A. Langerhans cell histiocytosis, MAP2K1

B. Rosai-Dorfman disease, BRAF V600E

C. Rosai-Dorfman disease, MAP2K1

D. Langerhans cell histiocytosis, BRAF V600E



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4 photo(s) Updated on: 09/18/2022

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